I am 41 and tried almost every kind of anti depression medication, been hospitalized 8 times, had ECT sessions, had over 20 psychiatrists, and nothing "legal" works.
Only one thing works and that's psilocybin magic mushrooms, which is truly life changing. Just difficult to get hold off. Haven't been able to get some during this lock down time. Can't wait to get my hands on some more.

@Tromills No? Are those the ones that grow wild in cow patties? I had a friend of mine die from those. There is no “ controlled dosage” One small one may contain a large concentration of the drug. Geeez. Be careful.